Revolutionizing Feminine Wellness: A Clinical Perspective on Fotona IntimaLase, Fotona Incontilase and Polynucleotide Synergy
- Dr. Khor See Ming
- 5 days ago
- 3 min read

Vaginal laxity and stress urinary incontinence (SUI) are prevalent conditions that significantly impact female quality of life, yet remain underdiagnosed and undertreated due to stigma or lack of accessible, non-surgical solutions. With the rise of functional aesthetic gynecology, non-invasive laser platforms such as Fotona’s IntimaLase® and IncontiLase® are leading a paradigm shift toward safe, effective, and evidence-based management.
Both treatments utilize non-ablative Er:YAG laser technology to remodel the vaginal mucosa and underlying collagen architecture, improving structural support and tissue tone. The recent addition of polynucleotide (PN) therapy further enhances outcomes by supporting cellular regeneration and hydration at the molecular level.
The Shift Toward Non-Invasive Intimate Rejuvenation
Traditionally, surgical vaginoplasty was the only option for women seeking vaginal tightening. While effective, it comes with surgical risks, downtime, and often psychological hesitation.
Today’s patient is different—she is informed, proactive, and seeking solutions that blend efficacy with comfort and minimal disruption to daily life. Non-invasive approaches like IntimaLase are quickly becoming the preferred choice.
Mechanism of Action : Er:YAG Non-Ablative Photothermal Effect
Fotona’s SMOOTH® mode delivers Er:YAG laser (wavelength 2940 nm) in a non-ablative, sub-ablative thermal mode, specifically designed for mucosal application.
The energy is delivered in microsecond pulses with precise thermal control, inducing homogeneous heating of the vaginal mucosa to 42–45°C.
This controlled photothermal effect denatures collagen triple helices, causing immediate contraction and stimulating fibroblast activity for neocollagenesis. The submucosa and lamina propria undergo structural remodeling, enhancing tissue elasticity, vascularity, and hydration.
The result is improved vaginal tone and support, achieved without epithelial disruption, ensuring rapid recovery and high patient tolerability.

Fotona IntimaLase®: Non-Invasive Vaginal Tightening
IntimaLase targets patients with vaginal laxity—often a result of childbirth, aging, or estrogen decline.
The treatment focuses on:
Thickening and tightening of the vaginal canal
Improved friction during sexual activity
Restoration of structural support to the pelvic floor
Fotona IncontiLase®: Treatment for Mild to Moderate SUI
IncontiLase is indicated for women with stress urinary incontinence, particularly those in early stages (Grade I–II) or with post-partum urethral hypermobility. The treatment protocol uses the same Er:YAG laser in a modified pattern to target:
Anterior vaginal wall
Paraurethral tissue
Bladder neck support structures
The heat-induced remodeling improves urethral closure pressure and bladder neck positioning during increased abdominal pressure.


Introducing Polynucleotides: A Regenerative Upgrade
While laser therapy stimulates the body’s own collagen production, polynucleotides (PNs) offer an added layer of regenerative support. Extracted and purified from salmon DNA, PNs are long-chain molecules with several therapeutic benefits:
Bio-stimulation of fibroblasts, promoting enhanced collagen and elastin synthesis.
Tissue regeneration, by supporting cell proliferation and repair.
Hydration through strong water-binding properties, improving mucosal health.
Anti-inflammatory effects, which soothe laser-treated tissue and support faster recovery.
Polynucleotides have long been used in ophthalmology and dermatology. Now, their application in gynecology—particularly following procedures like laser, radiofrequency, or microneedling—is showing promising results.
The Synergistic Protocol: Why Combine PN with Fotona
At Dream Clinic, we’ve developed a combined protocol that leverages Fotona Laser for structural tightening, followed by intravaginal or peri-vaginal polynucleotide application or injection for regenerative support.
Benefits of the combination:
Faster recovery: PNs reduce post-laser inflammation, leading to less discomfort and shorter healing times.
Amplified results: Enhanced fibroblast activity supports more robust tissue remodeling.
Better mucosal integrity: PNs improve hydration, texture, and function of the vaginal lining.
Longer-lasting outcomes: Tissue quality is sustained, reducing the frequency of maintenance sessions.
Who Benefits Most?
The ideal candidate for this treatment combination includes women experiencing:
Vaginal laxity post-partum or post-menopause
Mild to moderate stress urinary incontinence
Decreased sexual satisfaction due to laxity
Recurrent vaginal dryness or mucosal atrophy
Those seeking rejuvenation without surgery
Most patients benefit from 2–3 sessions spaced 4–6 weeks apart, with touch-up treatments annually.
The Future of Feminine Wellness
As the demand for functional aesthetic treatments grows, combining laser-based collagen induction with regenerative biotherapy offers an exciting new frontier. The synergy between technology (Fotona) and biologic regeneration (PNs) brings us closer to delivering personalized, holistic, and science-backed care to women across all life stages.
If you're a patient seeking a solution for intimate wellness concerns, I warmly invite you to book a consultation with me, Dr. Eunice, at Dream Clinic. With a commitment to evidence-based practice, cutting-edge technology, and compassionate care, I’m here to help guide you on a personalized and discreet journey to restored comfort, function, and confidence.

Reference:
Vizintin, Z., Rivera, M., Fistonić, I., Guimares, P., Gaviria, J., Garcia, V., Lukac, M., Perhavec, T., & Marini, L. (2012c). Novel Minimally Invasive VSP Er:YAG Laser Treatments in Gynecology. Journal of Laser and Health Academy. 2012.46-58. http://sanomed.com.tr/wp-content/uploads/2015/05/ErYAGinGynecology.pdf