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Writer's pictureDr. Khor See Ming

PRF and Microneedling: What’s the Hype?



Platelet-rich plasma (PRP) has paved the way for transformative solutions in various fields, spanning from dental, oral surgery, orthopedics, sports medicine to dermatology and aesthetics. The media-induced popularity of the ‘Vampire Facelift’, an effective skin rejuvenation treatment using PRP has consistently delivered high satisfaction. However, in the realm of aesthetics today, platelet-rich-fibrin (PRF) emerges as the upgraded version, offering enhanced benefits for skin repair and rejuvenation compared to PRP. With its cost-effectiveness, ready availability for both patients and practitioners, minimal downtime and side-effects, PRF stands out as an attractive treatment option for all skin types.


PRP and PRF are natural growth factors present in your own blood, functioning to initiate new cell growth, regenerate healing and stimulate collagen production. The key difference between PRP and PRF treatments lies primarily in the blood collection process prior to treatment, and the centrifuge spinning speed. PRF is spun at a lower speed, resulting in fewer damaged cells and a higher concentration of healing platelets. In comparison, PRF contains approximately 10 times the platelet concentration found naturally in the body, whereas PRP typically contains roughly 2-5 times that concentration.



Furthermore, another notable difference lies in the use of anticoagulants (substances used to prevent blood from clotting during injection) while preparing the blood products. With PRF, no anticoagulants are added, allowing for the creation of a spongy matrix that signals the platelets to release their growth factors gradually. Unlike PRP, which releases growth factors for a few hours, PRF continues to release them for up to a week. This gradual release contributes to more robust and longer-lasting results. The presence of fibrin and the extended-release of growth factors in PRF work to build volume in the skin, making it a favorable alternative as a biofiller, compared to synthetic fillers.




Where PRF Fits in with Antiaging


PRF is a treatment that, upon administration, preserves epidermal integrity while inducing notable epidermal and dermal changes for skin rejuvenation. Skin aging process is often accompanied by a reduction in collagen and hyaluronic acid, leading to a loss of skin firmness, worsening thinness and sagging. Most antiaging treatments target the dermis through microinjury to stimulate fibroblasts– cells responsible for collagen and elastin production in your skin, PRF takes a unique approach. Numerous studies have indicated that the growth factors within platelets contribute to improving various aspects of skin appearance including texture, color homogeneity, firmness, elasticity, solar elastosis, wrinkles, volume, dermal thickness, nasolabial fold severity, acne scars, erythema, melanin levels and overall patient satisfaction.



PRF + Microneedling : Your Skin Symphony


Platelet-Rich Fibrin (PRF) and microneedling form a dynamic duo in the world of skincare, working together in perfect harmony to deliver unparalleled results. Also known as ‘collagen induction therapy’, microneedling stands out as one of the most sought-after skin treatments among patients. This medical-grade procedure employs tiny needles to create controlled micro-channel injuries in the skin, prompting a natural healing response. Introducing PRF

into this narrative adds a superheroic element–loaded with growth factors and platelets that significantly enhance the regenerative process. Imagine your skin as a garden, and your face is the fertile soil where the flowers of youth and radiance bloom. Microneedling is like the gentle tilling of the soil, creating tiny channels for nutrients to penetrate deeply. Now, think of Platelet-Rich Fibrin (PRF) as the nourishing rain that falls upon this garden. Just as rain carries essential elements for plant growth, PRF brings a concentrated blend of your body's own healing components to enhance the rejuvenation process.


Image from Freepik


At-home vs In-Clinic Microneedling


While microneedling has become increasingly popular and accessible for at-home use, it is important to recognize the potential risks associated with the available DIY kits and non-medical beauty spa products. Their safety and efficacy may not align with the standards maintained by licensed professionals in clinical settings.

Allow me to explain why at-home microneedling can pose risks:

  1. Risk of Overuse: Overusing microneedling at home can irritate the skin, potentially exacerbating skin concerns and causing discomfort. This could lead to worsened hyperpigmentation or the development of post-inflammatory hyperpigmentation.

    Image courtesy: https://int.eucerin.com/about-skin/indications/hyperpigmentation-caused-by-inflammation

  2. Lack of Sterility: Microneedling at home without proper sterility measures may inadvertently spread infections, including warts, herpes, and other viruses, across the skin.

    Image courtesy: https://www.chemistclick.co.uk/news/herpes-rash


  3. Potential for Damage: Deep microneedling, if not done with precision, has the potential to damage the skin and result in scarring or alterations to the skin's color and texture.

    Image from Freepik



Who is not the candidate for PRF and microneedling?


While PRF and microneedling are generally safe and effective for many individuals, there are specific conditions and situations where they are not recommended or suitable. Pregnant women, for instance, are advised to avoid these procedures, as PRF and microneedling have not been thoroughly studied in this population. If you have a blood clotting disorder, blood cancer, or are taking blood-thinning medications, these treatments may not be suitable for you.


Additionally, individuals with active skin infections or inflammation, such as herpes or bacterial infections, should refrain from PRF and microneedling, as these procedures could potentially exacerbate these issues. Furthermore, those with a predisposition to keloid scarring, characterized by abnormal scar formation, may need to avoid microneedling, as the procedure has the potential to stimulate further scarring. It's crucial to consult with a healthcare professional to determine whether PRF and microneedling are appropriate for your specific health circumstances.



Nutshell


In conclusion, the combination of Platelet-Rich Fibrin (PRF) and microneedling represents a powerful synergy in the realm of dermatological and aesthetic treatments. By harnessing the regenerative properties of PRF and the controlled micro-injuries induced by microneedling, this innovative approach promotes collagen synthesis, tissue repair, and overall skin rejuvenation. Entrusting your PRF with microneedling treatments to the expertise of a skilled practitioner in the controlled environment of a licensed clinic guarantees not only a safe experience but also optimal results. Recognizing that your skin's health is an investment, you are welcome to schedule an appointment with me Dr Eunice at Dream Clinic to ensure a secure and effective journey toward achieving radiant and rejuvenated skin.




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