Cracked No More : PRF Therapy for Restoring Healthy Hands
- Dr. Amaani
- Apr 15
- 3 min read

Image from Shutterstock
Hand eczema, also known as hand dermatitis, is a common skin condition that causes redness, itching, dryness, and painful cracks on the hands. For many people, it’s a chronic issue that disrupts daily activities and affects confidence. Hand eczema is a multifactorial condition, meaning it can have several triggers, such as:
• Irritants: Prolonged exposure to soaps, detergents, or chemicals.
• Allergens: Contact with substances that trigger an allergic reaction.
• Genetics: A family history of eczema or atopic dermatitis.
• Dry Weather: Cold, dry climates can exacerbate symptoms.
While traditional treatments like moisturizers, corticosteroids, and emollients can provide relief, they often fall short in addressing the root cause and restoring skin health. These treatments often focus on symptom relief rather than promoting long-term healing.
What is PRF?
In recent years, Platelet-Rich Fibrin (PRF) has emerged as a promising regenerative treatment for hand eczema. It is a therapy derived from your own blood leveraging the body’s natural healing factors which contains a high concentration of platelets, growth factors, white blood cells, and fibrin. PRF offers a non-invasive and effective solution for improving skin texture, hydration, and overall health. Unlike its predecessor, Platelet-Rich Plasma (PRP), PRF is processed without anticoagulants, resulting in a slower release of growth factors for sustained healing and rejuvenation.

How PRF Benefits Hand Eczema
PRF is particularly effective for hand eczema because it addresses the underlying issues of inflammation, damaged skin, and impaired healing.
Promotes Skin Regeneration
The growth factors in PRF stimulate the production of collagen and elastin, essential for repairing damaged skin. This leads to the formation of healthier, more resilient skin over time.
Reduces Inflammation
PRF contains white blood cells, which play a crucial role in modulating inflammation and supporting the immune response. This helps to calm irritated skin and reduce redness.
Enhances Skin Hydration
By improving microcirculation and encouraging new capillary formation, PRF boosts hydration levels in the skin, alleviating dryness and cracking.
Accelerates Wound Healing
For patients with severe hand eczema, PRF can expedite the healing of open wounds or fissures, minimizing the risk of infection.
Natural and Safe
Since PRF is derived from your own blood, there’s no risk of allergic reactions or adverse effects, making it an ideal option for individuals with sensitive skin.
What to Expect With PRF Treatment
PRF is a minimally invasive procedure with little to no downtime. You will notice gradual improvements in skin texture, hydration, and elasticity over the next weeks as collagen and tissue repair take place. For optimal results, 2–3 sessions spaced 4–6 weeks apart may be recommended.
Is PRF Right for You?
Hand eczema can be a frustrating and painful condition, but treatments like PRF offer a new lease on life for those struggling with chronic symptoms. By harnessing the body’s natural healing abilities, PRF is an excellent option for individuals looking for a natural, safe, and effective way to treat hand eczema. PRF provides long-lasting relief, improved skin quality, and a boost in confidence.
If you’re ready to explore PRF as a treatment for hand eczema, book a consultation with Dream Clinic today. Let us help you regain healthier, happier hands.

References
Guidelines for the diagnosis, treatment, and prevention of hand eczema∗. (2019). Guidelines for the Diagnosis, Treatment, and Prevention of Hand Eczema∗, J.F. Silvestre Salvador,a,∗ F. Heras Mendaza,b M. Hervella Garcés,c D. Palacios-Martínez,d R. Sánchez Camacho,e R. Senan Sanz,f A. Apellaniz González,g A.M. Giménez-Arnau.
Vafaei-Nodeh, S., & Kabiri-Abyaneh, S. (2020). Long-term control of atopic dermatitis with platelet-rich plasma. JAAD Case Reports, 7, 54–56. https://doi.org/10.1016/j.jdcr.2020.10.036
Kauhl, W., Pototschnig, H., & Paasch, U. (2021). Can Platelet-Rich plasma reduce the burden of inflammatory skin diseases such as psoriasis and atopic dermatitis? Cureus. https://doi.org/10.7759/cureus.18472